Epigenetics and System Biology of Stem cells and Reprogramming


  1. Workshop 1: Bioinformatics

    City:       Istanbul
    Date:     November 11-14
    Hosted by EpiGenetiks, Turkey.
    The workshop will provide the ESRs with basic bioinformatic tools and concentrate on the analysis of epigenetics-related datasets, including (a) DNA mehylation and hydroxymethylationanalysis, (b) ChIP-seq and RNA-seq analysis (c) Mathematical modelling techniques in epigenomics in health and disease.


    Bioinformatics Workshop Istanbul.pdf
  2. Workshop 2: Epigenetics and Chromatin: processes and mechanisms

    City:        Munich
    Date:      April  3-5
    To be hosted by Helmholz Centrum .


    The workshop will be organised by Torres-Padilla, who also organised two previous meetings of the series in Strasbourg together with Abcam (2012, 2014). Main topics will include (a) Epigenomics and single cell approaches (b) histone, RNA and DNA modifications (c) Epigenetic phenomena (d) Reprogramming and stem cells.


    Workshop Munich.pdf
  3. Workshop 3: Single cell & MS Technologies

    Date:     1 – 5  August 2019
    To be hosted by Hubrecht Institute and Radboud University, the Netherlands.


    The workshop will be constructed of two parts: (a) Cutting-edge single cell technologies for transcriptomics and epigenomics focusing on DNA methylation and hydroxymethylation, (b) State-of-the-art proteomics technologies, focusing on methods which could be readily implemented in the ESRs’ research.


  4. Workshop 4: Reprogramming and disease modelling

    Date:      February 2020
    To be hosted by The University of Milan, Italy.


    The Workshop will include hands-on experimental work; discuss aspects of (a) reprogramming techniques, (b) chromatin remodelling and iPS cells. (c) The fundamental principles of reprogramming cells to pluripotency and the power of modelling neurological diseases using pluripotent models. Supplementary session: Ethical issues in reprogramming.
  5. Workshop 5: ES/iPS cells

    Date:      June 2020
    To be hosted by KadimaStem, Israel.


    The workshop will focus on the major aspects of stem cell research: (a) advanced methods of differentiation (b) stem cell drug screen platform technologies (c) regenerative medicine. A special session will be dedicated to the pharmaceutical industry, trends and directions.
    This workshop will be supplemented with 2 special sessions:
    • Training on communication and public engagement skills by Ben-Horin Alexandrovitch ibh.co.il
    • Training conducted by a professional organisational consultant.
  6. International conference on stem cell epigenetics

    Place:        University of Milan
    Date:          September 2020
    To be held at the University of Milan, Italy and organised by Meshorer, Testa and Almouzni.


    It will focus on the variety of the topics investigated by EpiSyStem network. The conference will open its doors not only to all ESRs, Network partners and members of the supervisory board, but will bring additional internationally acclaimed experts to present their science and engage in active discussions with the students. Applications from international students in the field of stem cell epigenetics will also be encouraged and “flash talks” / “elevator pitch” techniques will enable short presentations of posters. Activities such as ‘Meet the expert lunch’, meetings with journal editors, industry representatives, as well as group discussions will be held during this conference.
  7. An international annual course on epigenetics

    Place:        Institut Curie
    Date:         January 2021
    To be given at Institut Curie and co-organised by EpiSyStem member Almouzni – a past organiser of the Spetses Summer School.


    This 5-days course, now reaching its 12th year, focusing on Chromatin Dynamics and Epigenetics and is aimed to give an overview of epigenetic mechanisms and their link to chromatin dynamics. The course grants its students participants with 6 ECTS-credit points, and is recognised by most of the academic institutions as part of a PhD course duties. Seats for EpiSyStem members will be reserved. The course covers the following subjects which are all directly related to EpiSyStem: (a) Epigenetics and Chromatin Dynamics (b) Imaging the Nucleus and its function (c) Silencing, transcriptional landscapes and genomics (d) Memory of transcriptional states, stem cells and reprogramming (e) Epigenetics:
    Quantitative approaches and theoretical models (f) Maintenance of epigenome integrity (g) Epigenetics and cancers. In addition, a round table career development workshop will be held on the last day, involving contact with industrial parties and information to various career tracks.
  8. The Jerusalem School in Life Sciences

    Place:        Hebrew University of Jerusalem
    Date:         April 2021
    An annual Summer School at the Hebrew University of Jerusalem reaching now its 23rd year.


    The school is organised by EpiSyStem SAB member and Nobel Laureate Prof. Roger Kornberg (Stanford) and co-organised by Meshorer. The Summer School deals with different aspects of chromatin, nuclear dynamics and Eukaryotic transcription. This School will be open to and will hold seats for all EpiSyStem’s ESRs.
  9. Workshop 6: Epigenetics

    Date:      July 2021
    To be hosted by Diagenode, Belgium.


    The workshop will focus on epigenetic research in the industry. Main topics will cover (a) production and validation of ChIP-grade antibodies and reagents (b) epigenetics related technologies (c) entrepreneurship and the emerging epigenetic industry. Supplementary session: Intellectual property management in academia and industry.
Dec 5, 2019 @ 9:07
Fascinating paper from @gtesta72 describing the role of the chromatin remodeller BAZ1B in self domestication.
Congratulations to our EpiSyStem ESR Adrianos Skaros for this paper & looking forward to his future work on #epigenetics and #humanevolution. https://t.co/8OBDQ2MGZY https://t.co/6nMGuYiaPi
EpiSyStem_ITN photo
Dec 5, 2019 @ 2:20
An interview with Maria Elena Torres-Padilla ( @epigeneticsHMGU)
Maria, who joined us as an Editor last year, talked to @seemasainson about her career and the ties between the chromatin and #devbio fields
https://t.co/9LqGPpuKv1 https://t.co/mzhuwbJwUv
EpiSyStem_ITN photo
Dec 1, 2019 @ 11:55
@EpiSyStem_ITN congratulates @Cell2_Cell on its kickoff meeting and wishes you the best of luck! Looking forward for a fruitful cooperation with you guys! https://t.co/V7SIoJsPAv
EpiSyStem_ITN photo
Cell2Cell @Cell2_Cell
This week ITN Cell2Cell kicked off at @LMU_Muenchen: 13 PIs bringing together infection biology & yeast models, imaging & single-cell methods, bioinformatics & math. modeling to study cell-to-cell heterogeneity of chromatin structure. https://t.co/d8IJFl5yM7 @MSCActions https://t.co/9V6So50pDR
Nov 15, 2019 @ 8:19
My talk was about dispelling epigenetic myths. Scientists work so hard yet don't share it effectively & people remained misinformed (see eg). Being active in #scicomm is important to be a 'next gen scientist'. @EnableNetworkEU
#AcademicChatter #ENABLE2019 https://t.co/hu1dkg4A1J
EpiSyStem_ITN photo
Nov 15, 2019 @ 8:19
@EpiSyStem_ITN ESR @VelinSequeira stint at a pub talk talking about epigenetics. As an ITN, we actively support and encourage outreach activities #scicomm https://t.co/bvRssCNCMz
EpiSyStem_ITN photo
Velin Marita Sequeira @VelinSequeira
Amazing experience giving a pub talk #ENABLE2019. Science talks have a passive audience. But the pub talk peeps were so interactive & responsive, so much fun. Also, coming up with metaphors to explain concepts was an interesting challenge. 1/n https://t.co/ewHONqf5Tr



EpiSyStem is comprised of 8 leading academic partners and 2 professional industrial partners.

The Network combines chromatin biology in stem cells, early embryos and reprogramming, including the modelling of human neurological, chromatin-related diseases with bioinformatics, epigenetics / epigenomics, and systems biology at the population and single cell / single embryo level.

This multidisciplinary approach enables profound training and deep, systems-level understanding of chromatin biology and epigenetic regulation of stem cells, differentiation and reprogramming, with a strong support by industrial partners.